2,3-dihydroxyindole 2,3-dioxygenase
| 2,3-dihydroxyindole 2,3-dioxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.13.11.23 | ||||||||
| CAS no. | 37256-62-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
2,3-dihydroxyindole 2,3-dioxygenase (EC 1.13.11.23) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are 2,3-dihydroxyindole and oxygen. Its two products are anthranilic acid and carbon dioxide.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing). This enzyme participates in tryptophan metabolism.[1]
References
- ^ a b Enzyme 1.13.11.23 at KEGG Pathway Database.
- ^ Fujioka M, Wada H (1968). "The bacterial oxidation of indole". Biochim. Biophys. Acta. 158 (1): 70–8. doi:10.1016/0304-4165(68)90073-1. PMID 5652436.